RadTreeMap supports server-side binding to a data source control by setting the DataSourceID property. You can bind the TreeMap to various data source controls such as SqlDataSource, ObjectDataSource, XmlDataSource, etc.
Additionally, you should set DataTextField, DataValueField, DataFieldID, DataFieldParentID properties of RadTreeMap in order to match the desirable fields from the database table.
You may also find useful the following article: Server-side Data Binding.